Knockout of gene function via zygote injection of the CRISPR Cas-9 system. Homozygous and heterozygous available.
Publications:
Replacement of Porcine CD163 Scavenger Receptor Cysteine-Rich Domain 5 with a CD163-Like Homolog Confers Resistance of Pigs to Genotype 1 but Not Genotype 2 Porcine Reproductive and Respiratory Syndrome Virus
Genetic engineering alveolar macrophages for host resistance to PRRSV
Gene editing as applied to prevention of reproductive porcine reproductive and respiratory syndrome
Knockout of maternal CD163 protects fetuses from infection with porcine reproductive and respiratory syndrome virus (PRRSV)