Keeler SP, Yantis J, Gerovac BJ, Youkilis SL, Podgorny S, Mao D, Zhang Y, Whitworth KM, Redel B, Samuel MS, Wells KD, Prather RS, Holtzman MJ. Chloride channel accessory 1 (CLCA1) gene deficiency causes selective loss of mucus production in a new pig model. Am J Physiol Lung Cell Mol Physiol. 2022 Apr 19. doi: 10.1152/ajplung.00443.2021. Epub ahead of print. PMID: 35438004.

Chen PR, Rowland RRR, Stoian AM, Petrovan V, Sheahan M, Ganta C, Cino-Ozuna G, Kim DY, Dunleavey JM, Whitworth KM, Samuel MS, Spate LD, Cecil RF, Benne JA, Yan X, Fang Y, Croix BS, Lechtenberg K, Wells KD, Prather RS. Disruption of anthrax toxin receptor 1 in pigs leads to a rare disease phenotype and protection from senecavirus A infection. Sci Rep. 2022 Mar 23;12(1):5009. doi: 10.1038/s41598-022-09123-x. PMID: 35322150.

Rosa RH Jr, Xie W, Zhao M, Tsai SH, Hein TW, Kuo L. Intravitreal Administration of Stanniocalcin-1 Rescues Photoreceptor Degeneration with Reduced Oxidative Stress and Inflammation in a Porcine Model of Retinitis Pigmentosa. Am J Ophthalmol. 2022 Mar 17:S0002-9394(22)00111-8. doi: 10.1016/j.ajo.2022.03.014. Epub ahead of print. PMID: 35307380.

Schommer SK, Harrison N, Linville M, Samuel MS, Hammond SL, Wells KD, Prather RS. Serologic titers to Leptospira in vaccinated pigs and interpretation for surveillance. PLoS One. 2021 Nov 16;16(11):e0260052. doi: 10.1371/journal.pone.0260052. PMID: 34784395; PMCID: PMC8594815.

Chen PR, Redel BK, Kerns KC, Spate LD, Prather RS. Challenges and Considerations during In Vitro Production of Porcine Embryos. Cells. 2021;10(10):2770. Published 2021 Oct 15. doi:10.3390/cells10102770

Lucas CG, Redel BK, Chen PR, Spate LD, Prather RS, Wells KD. 2021. Effects of RAD51-Stimulatory Compound 1 (RS-1) and Its Vehicle, DMSO, On Pig Embryo Culture. Reprod Toxicol. 2021 Aug 15;S0890-6238(21)00129-5. doi: 10.1016/j.reprotox.2021.08.002. Online ahead of print. PMID: 34407461.

Nelson ED, Larson E, Joo DJ, Mao S, Glorioso J, Rmilah AA, Zhou W, Jia Y, Mounajjed T, Shi M, Bois M, Wood A, Jin F, Whitworth KM, Wells KD, Spate AM, Samuel MS, Minshew A, Walters EM, Rinaldo P, Lillegard J, Johnson A, Amiot B, Hickey R, Prather RS, Platt JL, Nyberg SL. 2021. Limited Expansion of Human Hepatocytesin FAH/RAG2-Deficient Swine. Tissue Eng Part A. 2021 July 26. doi:10.1089/ten.TEA.2021.0057. Online ahead of print. PMID:34309416.

Gabriel GC, Devine W, Redel BK , Whitworth KM, Samuel MS, Spate LD, Cecil RF, Prather RS, Wu Y, Wells KD, Lo CW. 2021. Cardiovascular Development and Congenital Heart Disease Modeling in the Pig. J Am Heart Assoc. 2021 Jul 3:e021631. doi: 10.1161/JAHA.121.021631. Online ahead of print. PMID: 34219463.

Koppes EA, Redel BK, Johnson MA, Skvorak KJ, Ghaloul-Gonzalez L, Yates ME, Lewis DW, Gollin SM, Wu YL, Christ SE, Yerle M, Leshinski A, Spate LD, Benne JA, Murphy SL, Samuel MS, Walters EM, Hansen SA, Wells KD, Lichter-Konecki U, Wagner RA, Newsome JT, Dobrowolski SF, Vockley J, Prather RS, Nicholls RD. 2020. A porcine model of phenylketonuria generated by CRISPR/Cas9 genome editing. JCI Insight. 2020 Oct15;5(20). PubMed PMID: 33055427; PubMed Central PMCID: PMC7605535.

Lucas, CG, Spate AM, Samuel MS, Spate LD, Warren WC, Prather RS, Wells KD. 2020. A novel swine sex-linked marker and its application across different mammalian species. Transgenic Res. 2020 Aug;29(4):395-407. doi: 10.1007/s11248-020-00204-z. Epub 2020 Jun 30. PubMed PMID: 32607872; PubMed Central PMCID: PMC7423754.

Cecil RF, Chen PR, Benne JA, Hord TK, Spate LD, Samuel MS, Prather RS. 2020. Chemical simulation of hypoxia in donor cells improves development of somatic cell nuclear transfer‐derived embryos and increases abundance of transcripts related to glycolysis. Mol Reprod Dev. 2020 Jun 17. doi: 10.1002/mrd.23392. Online ahead of print. PubMed PMID: 32558023; PubMed Central PMCID: PMC7496615.

Stoian A, Rowland RRR, Petrovan V, Sheahan M, Samuel MS, Whitworth KM, Wells KD, Zhang J, Beaton B, Cigan M, Prather RS. The use of cells from ANPEP knockout pigs to evaluate the role of aminopeptidase N (APN) as a receptor for porcine deltacoronavirus (PDCoV). Virology. 2020 Feb;541:136-140. doi: 10.1016/j.virol.2019.12.007. Epub 2019 Dec 24. PMID: 32056711; PMCID: PMC7112016.

Lucas CG, Chen PR, Seixas FK, Prather RS, Collares T. 2019. Applications of omics and nanotechnology to improve pig embryo production in vitro. Mol Reprod Dev. 2019 Nov;86(11):1531-1547. doi: 10.1002/mrd.23260. Epub 2019 Sep 3. Review. PubMed PMID: 31478591; PubMed Central PMCID: PMC7183242.

Kim SC, Mathews DV, Breeden CP, Higginbotham LB, Ladowski J, Martens G, Stephenson A, Farris AB, Strobert EA, Jenkins J, Walters EM, Larsen CP, Tector M, Tector AJ, Adams AB. 2019. Long-term survival of pig-to-rhesus macaque renal xenografts is dependent on CD4 T cell depletion. Am J Transplant. 2019 Aug;19(8):2174-2185. doi: 10.1111/ajt.15329. Epub 2019 Apr 5. PMCID: PMC6658347.

Mordhorst BR, Benne JA, Cecil RF, Whitworth KM, Samuel MS, Spate LD, Murphy CN, Wells KD, Green JA, Prather RS. 2019. Improvement of in vitro and early in utero porcine clone development after somatic donor cells are cultured under hypoxia. Mol Reprod Dev. 2019 May;86(5):558-565. doi: 10.1002/mrd.23132. Epub 2019 Feb 19. PMCID: PMC6510642.

Redel BK, Spate LD, Prather RS. 2019. In Vitro Maturation, Fertilization, and Culture of Pig Oocytes and Embryos. Methods in Mol Biol. 2019 2006:93-103. doi: 10.1007/978-1-4939-9566-0_6. PMID: 31230274.

Lim RR, Grant DG, Olver TD, Padilla J, Czajkowski AM, Schnurbusch TR, Mohan RR, Hainsworth DP, Walters EM, Chaurasia SS. 2018. Young Ossabaw Pigs Fed a Western Diet Exhibit Early Signs of Diabetic Retinopathy. Invest Ophthalmol Vis Sci. 2018 May 1;59(6):2325-2338. doi: 10.1167/iovs.17-23616. PMCID: PMC5937800.

Olver TD, Grunewald ZI, Jurrissen TJ, MacPherson RE, LeBlanc PJ, Schnurbusch TR, Czajkowski AM, Laughlin MH, Rector RS, Bender SB, Walters EM, Padilla J. 2018. Microvascular insulin resistance in skeletal muscle and brain occurs early in the development of juvenile obesity in pigs. Am J Physiol Regul Integr Com Physiol. 2018 Feb 1;314(2):R252-R264. doi: 10.1152/ajpregu.00213.2017. Epub 2017 Dec 4. PMCID: PMC5867673.

Walters EM, Burlak C. 2017. Xenotransplantation literature update, September/October 2017. Xenotransplantation. 2017 Nov;24(6). doi: 10.1111/xen.12367. Epub 2017 Nov 22. PMID:29168238.

Prather RS, Wells KD, Whitworth KM, Kerrigan MA, Samuel MS, Mileham A, Popescu LN, Rowland RRR. Knockout of maternal CD163 protects fetuses from infection with porcine reproductive and respiratory syndrome virus (PRRSV). Sci Rep. 2017 Oct 17;7(1):13371. doi: 10.1038/s41598-017-13794-2. PMID: 29042674; PMCID: PMC5645351.

Yang J, Menges S, Gu P, Tongbai R, Samuel M, Prather RS, Klassen H. Porcine neural progenitor cells derived from tissue at different gestational ages can be distinguished by global transcriptome. Cell Transplant. 2017 Sep;26(9):1582-1595. doi: 10.1177/0963689717723015. PMCID: PMC5524599.

Walters EM, Kerns K, Burlak C. 2017. Xenotransplantation literature update, May/June 2017. Xenotransplantation. 2017 Jul;24(4). doi: 10.1111/xen.12323. Epub 2017 Jul 25. PMID: 28741697.

Yuan, Y, Spate LD, Redel BK, Tian Y, Zhou J, Prather RS, Roberts RM. Quadrupling efficiency in production of genetically modified pigs through improved oocyte maturation. Proc Natl Acad Sci USA. 2017 Jul 18;114(29):E5796-E5804. doi: 10.1073/pnas.1703998114. Epub 2017 Jul 3. PMCID: PMC5530680.

Wells KD, Prather RS. 2017. Genome-editing technologies to improve research, reproduction, and production in pigs. Mol Reprod Dev. 2017 Sep;84(9):1012-1017. doi: 10.1002/mrd.22812. Epub 2017 Jun 8. PMCID: PMC5603364.

Whitworth KM, Prather RS. Gene editing as applied to prevention of reproductive porcine reproductive and respiratory syndrome. Mol Reprod Dev. 2017 Sep;84(9):926-933. doi: 10.1002/mrd.22811. Epub 2017 Jun 8. PMID: 28390179.

Walters EM, Asnaf SE, Burlak C. 2017. Xenotransplantation literature update, March/April 2017. Xenotransplantation. 2017 May;24(3). doi: 10.1111/xen.12316. PMID: 28593725.

Scott PA, Fernandez de Castro JP, DeMarco PJ, Ross JW, Njoka J, Walters E, Prather RS, McCall MA, Kaplan HJ. 2017. Progression of Pro23His retinopathy in a miniature swine model of retinitis pigmentosa. Transl Vis Sci Technol. 2017 Mar 15;6(2):4. doi: 10.1167/tvst.6.2.4. eCollection 2017 Mar. PMCID: PMC5354474.

Prather RS, Whitworth KM, Schommer SK, Wells KD. Genetic engineering alveolar macrophages for host resistance to PRRSV. Vet Microbiol. 2017 Sep;209:124-129. doi: 10.1016/j.vetmic.2017.01.036. Epub 2017 Feb 10. PMID: 28215617.

Wells KD, Bardot R, Whitworth KM, Trible BR, Fang Y, Mileham A, Kerrigan MA, Samuel MS, Prather RS, Rowland RRR. Replacement of Porcine CD163 Scavenger Receptor Cysteine-Rich Domain 5 with a CD163-Like Homolog Confers Resistance of Pigs to Genotype 1 but Not Genotype 2 Porcine Reproductive and Respiratory Syndrome Virus. J Virol. 2017 Jan 3;91(2):e01521-16. doi: 10.1128/JVI.01521-16. PMID: 27847356; PMCID: PMC5215333.

Whitworth KM, Benne JA, Spate LD, Murphy SL, Samuel MS, Murphy CN, Richt JA, Walters E, Prather RS, Wells KD. 2017. Zygote injection of CRISPR/Cas9 RNA successfully modifies the target gene without delaying blastocyst development or altering the sex ratio in pigs. Transgenic Res. 2017 Feb;26(1):97-107. doi: 10.1007/s11248-016-9989-6. Epub 2016 Oct 15. PMCID: PMC5247313.

Choi YJ, Lee K, Park WJ, Kwon DN, Park C, Do JT, Song H, Cho SK, Park KW, Brown AN, Samuel MS, Murphy CN, Prather RS, Kim JH. 2016. Partial loss of interleukin 2 receptor gamma function in pigs provides mechanistic insights for the study of human immunodeficiency syndrome. Oncotarget. 2016 Aug 9;7(32):50914-50926. doi: 10.18632/oncotarget.10812. PMCID: PMC5239447.

Redel BK, Prather RS. 2016. Meganucleases revolutionize the production of genetically engineered pigs for the study of human diseases Toxicol Pathol. 2016 Apr;44(3):428-33. doi: 10.1177/0192623315613160. Epub 2015 Oct 28. PMCID: PMC4805444.

Lee W, Miyagawa Y, Long C, Ekser B, Walters E, Ramsoondar J, Ayares D, Tector AJ, Cooper DK, Hara H. 2016. Expression of NeuGc on pig corneas and its potential significance in pig corneal xenotransplantation. Cornea. 2016 Jan;35(1):105-13. doi: 10.1097/ICO.0000000000000635. PMCID: PMC4847538.

Lee K, Davis A, Zhang L, Spate LD, Park K-W, Samuel MS, Walters EM, Murphy CN, Machaty Z, Prather RS. 2015. Pig oocyte activation utilizing a Zn2+ chelator, TPEN. Theriogenology. 2015 Oct 1;84(6):1024-32. doi: 10.1016/j.theriogenology.2015.05.036. Epub 2015 Jun 12. PMCID: PMC4553067.

Beaton BP, Kwon DN, Choi YJ, Kim JH, Samuel MS, Benne JA, Wells KD, Lee K, Kim JH, Prather RS. 2015. Inclusion of homologous DNA in nuclease-mediated gene targeting facilitates a higher incidence of bi-allelically modified cells. Xenotransplantation. 2015 Sep-Oct;22(5):379-90. doi: 10.1111/xen.12194. PMCID: PMC4584494.

Zhao J, Xu W, Ross JW, Walters EM, Butler SP, Whyte JJ, Kelso L, Fatemi M, Vanderslice NC, Giroux K, Spate LD, Samuel MS, Murphy CN, Wells KD, Prather RS, Masiello N, Velander WH. 2015. Engineering protein processing of the mammary gland to produce abundant hemophilia B therapy in milk. Sci Rep. 2015 Sep 21;5:14176. doi: 10.1038/srep14176. PMCID: PMC4585688.

Donninger H, Hobbing K, Schmidt ML, Walters E, Rund L, Schook L, Clark GJ. 2015. A porcine model system of BRCA1 driven breast cancer. Front Genet. 2015 Aug 25;6:269. doi:10.3389/fgene.2015.00269. eCollection 2015. PMCID: PMC4548227.

Whitworth KM, Mao J, Lee K, Spollen WG, Samuel MS, Walters EM, Spate LD, Prather RS. 2015. Transcriptome analysis of pig in vivo, in vitro fertilized and nuclear transfer blastocyst stage embryos treated with histone deacetylase inhibitors post-fusion and activation reveals changes in the lysosomal pathway. Cell Reprogram. 2015 Aug;17(4):243-58. doi: 10.1089/cell.2015.0022. PMCID: PMC4529055.

Schook LB, Collares TV, Hu W, Lian Y, Rodrigues FM, Rund LA, Schachtschneider KM, Seixas FK, Singh K, Wells KD, Walters EM, Prather RS, Counter CM. 2015. A genetic porcine model of cancer. PLoS One. 2015 Jul 1;10(7):e0128864. doi: 10.1371/journal.pone.0128864. eCollection 2015. PMCID: PMC4488487.

Park J, Lai L, Samuel MS, Wax D, Prather RS, Tian X. 2015. Disruption of Mitochondrion-To-Nucleus Interaction in Deceased Cloned Piglets. PLoS One. 2015 Jun 11;10(6):e0129378. doi: 10.1371/journal.pone.0129378. eCollection 2015. PMCID: PMC4466210.

Yang G, Artiaga BL, Hackmann TJ, Samuel MS, Walters EM, Salek-Ardakani S, Driver JP. 2015. Targeted disruption of CD1d prevents NKT cell development in pigs. Mamm Genome. 2015 Jun;26(5-6):264-70. doi: 10.1007/s00335-015-9564-0. Epub 2015 May 1. PMCID: PMC4830386.

Redel BR, Tessanne K, Spate LD, Murphy CN, Prather RS. 2015. Arginine increases development of in vitro produced embryos and affects the PRMT-DDAH-NO axis. Reprod Fertil Dev. 2015 May;27(4):655-66. doi: 10.1071/RD14293. PMCID: PMC4726483.

Men H, Spate LD, Murphy CN, Prather RS. 2015. Cryopreservation of in vitro-produced early stage porcine embryos in a closed system. BioRes Open Access. 2015 May 1;4(1):258-65. doi: 10.1089/biores. 2015.0012. eCollection 2015. PMCID: PMC4497712.

Spate LD, Brown AN, Redel BK, Whitworth KM, Prather RS. 2015. PS48 can replace bovine serum albumin in pig embryo culture medium, and improve in vitro embryo development by phosphorylating AKT. Mol Reprod Dev. 2015 Apr;82(4):315-20. doi: 10.1002/mrd.22474. Epub 2015 Mar 16. PMCID: PMC4720971.

Huang J, Zhang H, Wang X, Dobbs K, Yao J, Qin G, Whitworth KM, Walters EM, Prather RS, Zhao J. 2015. Preimplantation porcine embryo development impairment by histone demethylase KDM5B knockdown and disturbance of bi-valent H3K4me3-H3K27me3 modifications. Biol Reprod. 2015 Mar;92(3):72. doi: 10.1095/biolreprod.114.122762. Epub 2015 Jan 21. PMCID: PMC4367965.

Mao J, Zhao M-T, Whitworth KM, Spate LD, Walters EM, O’Gorman C, Lee K, Samuel MS, Murphy CN, Prather RS. 2015. Oxamflatin treatment enhances cloned porcine embryo development and nuclear reprogramming. Cell Reprogram. 2015 Feb;17(1):28-40. doi: 10.1089/cell.2014.0075. Epub 2014 Dec 30. PMCID: PMC4312790.

Prather RS, Walters EM, Wells KD. 2015. Proceedings of The Conference on “Swine in Biomedical Research 2014”. Lab Animal. 2015;44:9.

Whitworth KM, Lee K, Benne JA, Beaton BP, Spate LD, Murphy SL, Samuel MS, Mao J, O’Gorman C, Walters EM, Murphy CN, Driver JP, Mileham A, McLaren D, Wells KD, Prather RS. 2014. Use of the CRISPR/Cas9 system to produce genetically engineered pigs from in vitro derived oocytes and embryos. Biol Reprod. 2014 Sep;91(3):78. doi: 10.1095/biolreprod.114.121723. Epub 2014 Aug 6. PMCID: PMC4435063.

Li G, Jia Q, Zhao J, Li X, Yu M, Samuel MS, Zhao S, Prather RS, Li C. 2014. Dysregulation of genome-wide gene expression and DNA methylation in abnormal cloned piglets. BMC Genomics. 2014 Sep 24;15:811. doi: 10.1186/1471-2164-15-811. PMCID: PMC4189204.

Lee K, Kwon DN, Ezashi T, Choi YJ, Park C, Ericsson AC, Brown AN, Samuel MS, Park KW, Walters EM, Kim DY, Kim JH, Franklin CL, Murphy CN, Roberts RM, Prather RS, Kim JH. 2014. Engraftment of human iPS cells and allogeneic porcine cells into pigs with inactivated RAG2 and accompanying severe combined immunodeficiency. Proc Natl Acad Sci USA. 2014 May 20;111(20):7260-5. doi:10.1073/pnas.1406376111. PMCID: PMC4034252.

Tessanne K, Lee K, Prather RS. 2014. Genetically modified organisms in meat animal production. In: Devine C, Dikeman M, editors-in-chief. Encyclopedia of meat sciences, 2nd Ed, Vol. 1. Oxford: Elsevier; 2014. p. 92-96.

Prather RS, Rowland RR, Ewen C, Trible B, Kerrigan M, Bawa B, Teson JM, Mao J, Lee K, Samuel MS, Whitworth KM, Murphy CN, Egen T, Green JA. An intact sialoadhesin (Sn/SIGLEC1/CD169) is not required for attachment/internalization of the porcine reproductive and respiratory syndrome virus. J Virol. 2013 Sep;87(17):9538-46. doi: 10.1128/JVI.00177-13. Epub 2013 Jun 19. PMID: 23785195; PMCID: PMC3754101.

Spate LD, Murphy CN, Prather RS. 2013. High-throughput vitrification of in vivo produced porcine embryos. PLoS One. 2013 Jun 7;8(6):e65545. doi: 10.1371/journal.pone.0065545. PMCID: PMC3676344.
Prather RS. 2013. Pig genomics for biomedicine. News & Views. Nat Biotechnol. 2013 Feb;31(2):122-4. doi: 10.1038/nbt.2490. PMID: 23392511.

Walters EM, Prather RS. 2013. Advancing swine models for human health and disease. Mo Med. 2013 May-Jun;110(3):212-5. PMCID: PMID6179855.

Sutovsky P. 2013. Transgenic pig carrying green fluorescent proteasomes. Proc Natl Acad Sci USA. 2013 110:6334-6339. doi:10.1073/pnas.1220910110. Epub 2013 Apr 2. PMCID: PMC3631692.

Lee K, Prather RS. 2013. Chapter 19: Cloning pigs by somatic cell nuclear transfer. In: Cibelli J, Gurdon J, Wilmut I, Jaenisch R, Lanza R, West M, Campbell K, editors. Principles of cloning, 2nd Ed. Academic Press; 2013. p. 245-254.

Lee K, Prather RS. 2013. Advancements in somatic cell nuclear transfer and future perspectives. In: Nilsson M, Flowers W, editors. Animal Frontiers, fertility issue. 2013. p. 56-61.

Isom SC, Stevens JR, Li R, Spollen WG, Cox L, Spate LD, Murphy CN, Prather RS. 2013. Transcriptional profiling by RNA-Seq of peri-attachment porcine embryos generated by a variety of assisted reproductive technologies. Physiol Genomics. 2013 Jul 15;45(14):577-89. doi: 10.1152/physiolgenomics.00094.2012. PMCID: PMC3727017.

Spate LD, Murphy CN, Prather RS. 2013. High-throughput cryopreservation of in vivo-derived swine embryos. PLoS One. 2013 Jun 7;8(6):e65545. doi: 10.1371/journal.pone.0065545. PMCID: PMC3676344.

Kwon DN, Lee K, Kang MJ, Choi YJ, Park C, Whyte JJ, Brown AN, Kim JH, Samuel M, Mao J, Park KW, Murphy CN, Prather RS, Kim JH. 2013. Production of biallelic CMP-Neu5Ac hydroxylase knock-out pigs. Sci Rep. 2013 3:1981. doi: 10.1038/srep01981. PMCID: PMC4070623.

Beaton BP, Mao J, Murphy CN, Samuel MS, Prather RS, Wells KD. 2013. Use of single stranded targeting DNA or negative selection does not further increase efficiency of a GGTA1 promoter trap. J Mol Cloning Genet Recomb. 2013 Mar 27;2(1):684. doi: 10.4172/2325-9787.1000101. PMCID: PMC4190589.

Lee K, Redel BK, Teson J, Spate LD, Park K-W, Walters E, Samuel M, Murphy CN, Prather RS. 2013. Piglets produced from cloned blastocysts cultured in vitro with GM-CSF. Mol Reprod Dev. 2013 Feb;80(2):145-54. doi: 10.1002/mrd.22143. PMCID: PMC4392757.

Prather RS, Lorson M, Ross JW, Whyte J, Walters E. 2013. Genetically engineered pig models for human diseases. Annu Rev Anim 2013 Jan;1:203-19. doi: 10.1146/annurev-animal-031412-103715. Epub 2013 Jan 3. PMCID: PMC4460601.

Men H, Walters EM, Nagashima H, Prather RS. 2012. Emerging applications of sperm, embryo and somatic cell cryopreservation in maintenance, relocation and rederivation of swine genetics. Theriogenology. 2012 Nov;78(8):1720-9. doi: 10.1016/j.theriogenology.2012.06.003. Epub 2012 Aug 13. Review. PMCID: PMC3472131.

EM Walters, E Wolf, JJ Whyte, J Mao, S Renner, H Nagashima, E Kobayashi, J Zhao, KD Wells, JK Critser, LK Riley, RS Prather. 2012. Completion of the swine genome will simplify the production of swine as a large animal biomedical model. BMC Med Genomics. 2012 Nov 15;5:55. doi: 10.1186/1755-8794-5-55. PMCID: PMC3499190.

Mao J, Tessanne K, Whitworth KM, Spate LD, Walters EM, Samuel MS, Murphy CN, Tracy L, Zhao J, Prather RS. 2012. Effects of combined treatment of MG132 and scriptaid on early and term development of porcine somatic cell nuclear transfer embryos. Cell Reprogram. 2012 Oct;14(5):385-9. doi: 10.1089/cell.2012.0018. Epub 2012 Aug 23. PMCID: PMC3459054.

Mao J, Whitworth KM, Spate LD, Walters EM, Zhao J, Prather RS. 2012. Regulation of oocyte mitochondrial DNA copy number by follicular fluid, EGF, and neuregulin 1 during in vitro maturation affects embryo development in pigs. Theriogenology. 2012 Sep 1;78(4):887-97. doi: 10.1016/j.theriogenology.2012.04.002. Epub 2012 May 22. PMCID: PMC4714324.

Whyte, JJ, Prather RS. 2012. Zinc-finger nucleases to create custom-designed modifications in the swine (sus scrofa) genome. J. Anim Sci. 2012 Apr;90(4):1111-7. doi: 10.2527/jas.2011-4546. Epub 2011 Oct 28. PMID 22038991.

Yang X, Mao J, Walters EM, Zhao M, Teson J, Lee K, Prather RS. 2012. Xenopus Egg Extract Treatment Reduced Global DNA Methylation of Donor Cells and Enhanced Somatic Cell Nuclear Transfer Embryo Development in Pigs. Biores Open Access. 2012 Apr;1(2):79-87. doi: 10.1089/biores.2012.0214. PMCID: PMC3559225.

Ross JW, Fernandez de Castro JP, Zhao J, Samuel M, Walters EM, Rios C, Bray-Ward P, Jones BW, Marc RE, Wang W, Zhou L, Noel J, McCall M, DeMarco P, Prather RS, Kaplan HJ. 2012. Generation of an inbred miniature pig model of retinitis pigmentosa. 2012. Invest Ophthalmol Vis Sci. 2012 Jan 31;53(1):501-7. doi: 10.1167/iovs.11-8784. PMCID: PMC3292381.

Walters EM, Agca Y, Ganjam V, Evans T. 2011. Animal Models Got you Puzzled? Think Pig. Ann N Y Acad Sci. 2011 Dec;1245:63-4. doi: 10.1111/j.1749-6632.2011.06345.x. PMID: 22211982.

Whyte JJ, Samuel MS, Mahan E, Padilla J, Simmons GH, Arce-Esquivel AA, Bender SB, Whitworth KM, Hao YH, Murphy CN, Walters, EM, Prather, RS, and Laughlin, MH. 2011. Vascular endothelium-specific overexpression of human catalase in cloned pigs. Transgenic Res. 2011 Oct;20(5):989-1001. doi: 10.1007/s11248-010-9473-7. Epub 2010 Dec 18. PMCID: PMC3286124.

Richards MP, Kathirvel P, Gong Y, Lopez-Hernandez A, Walters EM, Prather RS. 2011. Long chain omega-3 fatty acid levels in loin muscle from transgenic (fat-1 gene) pigs and effects on lipid oxidation during storage. 2011. Food Biotechnology 25:103-114.

Men H, Zhao C, Si W, Murphy CN, Spate L, Liu Y, Walters EM, Samuel MS, Prather RS, Critser JK. 2011. Birth of piglets from in vitro produced, zona-intact porcine embryos vitrified in a closed system. 2011. Theriogenology. 2011 Jul 15;76(2):280-9. doi: 10.1016/j.theriogenology.2011.02.004. Epub 2011 Mar 31. PMCID: PMC3115500.

Whyte, JJ, Prather RS. 2011. Genetic modifications of pigs for medicine and agriculture. Mol Repro Dev. 2011. 78:879-891. NIHMSID #299529.

Whyte JJ, Zhao J, Wells KD, Samuel MS, Whitworth KM, Walters EM, Laughlin MH, Prather RS. 2011. Gene targeting with zinc finger nucleases to produce cloned eGFP knockout pigs. Mol. Reprod. Dev. 2011 Jan;78(1):2. doi: 10.1002/mrd.21271. PMCID: PMC4462126.

Whitworth, KM, Prather RS. 2010. Somatic cell nuclear transfer efficiency- Remodeling and reprogramming: How can it be improved? Mol Repro Dev. 2010 Dec;77(12):1001-15. doi: 10.1002/mrd.21242. Epub 2010 Oct 7. PMCID: PMC4718708.

Ross JW, Whyte JJ, Zhao J, Samuel M, Wells KD, Prather RS. 2010. Optimization of square-wave electroporation for transfection of porcine fetal fibroblasts. Transgenic Res. 2010 Aug;19(4):611-20. doi: 10.1007/s11248-009-9345-1. Epub 2009 Nov 24. PMCID: PMC2894267.

Zhao J, Whyte JJ, and Prather RS. 2010. Effect of epigenetic regulation during swine embryogenesis and on cloning by nuclear transfer. Cell Tissue Res. 2010 Jul;341(1):13-21. doi: 10.1007/s00441-010-1000-x. Epub 2010 Jun 20. PMID: 20563602.

Zhao J, Hao Y, Ross JW, Spate LD, Walters EM, Samuel MS, Rieke A, Murphy CN, Prather RS. 2010. Histone deacetylase inhibitors improve in vitro and in vivo developmental competence of somatic nuclei nuclear transfer porcine embryos. Cell Reprogram 2010 Feb;12(1):75-83. doi: 10.1089/cell.2009.0038. PMCID: PMC2842950.


Yang X, Mao J, Walters EM, Zhao M, Lee K, Prather RS. 2012. Treatment of donor cells with Xenopus oocyte extract enhanced SCNT embryo development. 38th Annual International Embryo Transfer Society. Phoenix, AZ.

Mao J, Whitworth KM, Spate LD, Walters EM, Zhao J, Prather RS. 2012. Supplementation of maturation medium with follicular fluid, Epidermal Growth Factor, and Neuregulin affects mitochondrial DNA replication, oocyte maturation, and embryo development in pigs. 38th Annual International Embryo Transfer Society. Phoenix, AZ.

Walters EM, Samuel MS, Wells KD, Riley LK, Prather RS. 2012. The Pig as a Biomedical Model-How the National Swine Resource and Research Center Can Help You. 38th Annual International Embryo Transfer Society. Phoenix, AZ. PMID:22394972.

Walters EM, Evans TJ, Agca Y, Ganjam VK. 2011. Development of a Porcine Model for Exposure to Endocrine Disrupting Chemicals. Animal Models and Their Value in Predicting Drug Efficacy and Toxicity. New York Academy of Sciences. New York City, New York.

Prather RS. 2011. Technical blocks to efficient pig cloning. CTS-IXA 2011 Joint International Congress, Miami, FL. Oct. 23-26.

Whyte JJ, Zhao J, Wells KD, Samuel MS, Whitworth KM, Walters EM, Laughlin MH, Prather RS. 2011. Zinc-finger nucleases: new innovations in custom-designed modification of the swine genome. Swine in Biomedical Research Conference July 17-19, Chicago, IL. P 27.

Beaton BP, Walters E, Prather RS, Wells K. 2011. Alpha-Galactosyltransferase (a1,3-Gal) Knockout Genetically Linked to Xenograft Transgenes. Swine in Biomedical Research Conference July 17-19, Chicago, IL. P 28.

Li C, O’Gorman C, Prather RS, Green JA, Wells KD. 2011. BWS symptoms in cloned piglets are associated with hypomethylation at the KCNQ-OT1 CpG island. Swine in Biomedical Research Conference July 17-19, Chicago, IL. P 35.

O’Gorman CW, Zhao J, Samuel MS, Walters EM, Prather RS, Sutovsky P, Sutovsky M, Wells KD. 2011.Swine in Biomedical Research Conference July 17-19, Chicago, IL. P 36.

Zhao JG, Walters EM, Calcaterra J, Kelso L, Giroux K, Samuel MS, Butler S, Velander WH, Prather RS, 2011. Increased propeptide processing of Factor IX in the milk of transgenic pigs by co-expression of Furin. Swine in Biomedical Research Conference July 17-19, Chicago, IL. P 41.

Whyte JJ, Prather RS, 2011. Zinc-Finger Nucleases: New Innovations in Custom-Designed Modification of the Swine Genome. ADSA-ASAS Annual Meeting.

Whitworth K, Teson J, Lee K, Mao J, Tessanne K, Spate LD, Prather RS. 2012. The histone deacetylase inhibitor 4-iodo-Suberoylanilide Hydroxamic Acid (I-SAHA) improves total cell number in pig nuclear transfer blastocysts. International Embryo Transfer Society Annual Meeting. Reprod. Fertil. & Devel. 24: 125.

Tessanne K, Bauer B, Whitworth K, Spate L, Brown A, Prather RS. 2012. Characterization of the PRMT-DDAH-NO axis during porcine embryo development International Embryo Transfer Society Annual Meeting. Reprod. Fertil. & Devel. 24:185.

Whyte JJ, Isom SC, Spollen WG, Blake SM, Walters EM, Prather RS. 2011. DNA methylome analysis in nuclear transfer cells and its relationship to cloning efficiency in swine. 37th Annual International Embryo Transfer Society. Orlando, FL.

O’Gorman C, Zhao J, Samuel M, Walters E, Prather R, Sutovsky P, Sutovsky M, Wells KD. 2011. Construction of a genetically engineered pig expressing GFP-labeled proteasomes. 37th Annual International Embryo Transfer Society. Orlando, FL.