Deletion in the RAG2 gene.
Donated by the National Swine Resource and Research Center, University of Missouri.
References:
- Lee K, Kwon DN, Ezashi T, Choi YJ, Park C, Ericsson AC, Brown AN, Samuel MS, Park KW, Walters EM, Kim DY, Kim JH, Franklin CL, Murphy CN, Roberts RM, Prather RS, Kim JH. 2014. Engraftment of human iPS cells and allogeneic porcine cells into pigs with inactivated RAG2 and accompanying severe combined immunodeficiency. Proc Natl Acad Sci USA. 2014 May 20;111(20):7260-5. doi:10.1073/pnas.1406376111. PMCID: PMC4034252.