NSRRC:0094 PSEN1 - National Swine Resource and Research Center

Inactivation of PSEN1 via the CRISPR-Cas9 system resulting in a model for Alzheimer’s Disease.

Uh, K., Monarch, K., Reese, E. D., Rodriguez, K., Yoon, J., Spate, L. D., Samuel, M. S., Koh, S., Chen, P. R., Jarome, T. J., Allen, T. A., Prather, R. S., & Lee, K. (2024). Impaired Skeletal Development by Disruption of Presenilin-1 in Pigs and Generation of Novel Pig Models for Alzheimer’s Disease. Journal of Alzheimer’s disease : JAD, 101(2), 445–461. https://doi.org/10.3233/JAD-231297