Strain Availability

To request swine or cryopreserved material from the NSRRC, please contact NSRRC@missouri.edu, at (573) 882-1134.

There are a variety of samples available from the strains listed below: A few examples are fetal fibroblast, fresh and cryopreserved semen, live animals, hearts, femurs, kidneys, liver, Day 50 eyes, and Day 60 fetal hearts. Please inquire about the sample request and availability; we should be able to meet your requests in a timely manner. All NSRRC strain distributions require an NSRRC Outgoing Material Transfer Agreement.

List of Available Strains

Stock # Strain Name Background Affected Gene(s) Availability Genomic Alteration
NSRRC:0001 Truline® Hampshire outbred N/A Cryopreserved wildtype
NSRRC:0002 Truline® Duroc outbred N/A Cryopreserved wildtype
NSRRC:0003 Truline® Landrace outbred N/A Cryopreserved wildtype
NSRRC:0004 Truline® Large White outbred N/A Cryopreserved wildtype
NSRRC:0005 Minnesota Mini closed population N/A Live-limited wildtype
NSRRC:0008 Ossabaw closed population N/A Currently unavailable wildtype
NSRRC:0009 GGTA1 knockout; CD55 closed population CD55 and GGTA1 Live GGTA1 knockout and CD55 transgene
NSRRC:0010 GFP NT5 outbred N/A Cryopreserved Transgene: CMV promoter driving eGFP
NSRRC:0011 FAT1 outbred FAT1 Cryopreserved Transgene: expression of hFAT1
NSRRC:0012 Yucatan closed population N/A Cryopreserved wildtype
NSRRC:0013 NIH Mini g/g inbred N/A Cryopreserved wildtype
NSRRC:0014 NIH Mini c/c inbred N/A Live-Very limited wildtype
NSRRC:0015 NIH Mini a/a inbred N/A Cryopreserved wildtype
NSRRC:0016 GFP NT92 outbred Green fluorescent Protein Live Transgene: CAG promoter driving the enhanced green fluorescent protein
NSRRC:0017 Rhodopsin NIHc/c RHO Live Transgene: Rhodopsin (RHO) P23H substitution
NSRRC:0018 FVIII outbred FVII, FURIN, SERPINA1 Cryopreserved Transgenes: Human coagulation factor VIII; Human alpha 1-antitrypsin; Propeptide cleavage enzyme (PACE/FURIN)
NSRRC:0019 FIX outbred FIX, FURIN, VWF Cryopreserved Transgenes: Human coagulation factor IX; Human alpha 1-antitrypsin; von Willibrand factor
NSRRC:0020 GFP Yucatan Yucatan Green fluorescent Protein Cryopreserved Transgene: CAG promoter driving the enhanced green fluorescent protein
NSRRC:0021 Tie2-eNOS Yucatan NOS3 Cryopreserved Transgene: Tie2 promoter driving endothelial Nitrate Oxide Synthase (NOS3)
NSRRC:0022 Tie2-Catalase Yucatan CAT Cryopreserved Transgene: Human Catalase (CAT)
NSRRC:0024 GFP-Proteasomes Minnesota Mini PSMA1 Cryopreserved Transgene: GFP-Proteasome Fusion Protein (PSMA1)
NSRRC:0025 Multi-Xeno outbred GGTA1, CD39, CD55, CD59 Cryopreserved GGTA1 knockout; with three randomly integrated transgenes: human decay-accelerating factor (CD55); CD39; CD59 and thrombomodulin
NSRRC:0026 NLS-CAG-eGFP Minnesota Mini Green Fluorescent Protein Cryopreserved Transgene: CAG promoter driving a Nuclear localized enhanced Green Fluorescent Protein
NSRRC:0027 CAG-Tomato Minnesota Mini tdTomato Cryopreserved Transgene: CAG promoter driving tdTomato
NSRRC:0028 ALP-CD outbred CDA Cryopreserved Transgene: Alpha fetoprotein (AFP) promoter driving cytidine deaminase (CDA)
NSRRC:0029 ALB-xTK outbred TK1 Cryopreserved Transgene: Albumin (ALB) promoter driving Thymidine Kinase (TK1)
NSRRC:0030 ZP3-Cre Minnesota Mini ZP3-CRE-GFP Cryopreserved Transgene: Zona Pecullida 3 (ZP3) promoter driving CRE-eGFP
NSRRC:0031 UBC-Tomato Minnesota Mini and Minnesota Mini/Domestic tdTomato Live-limited (MN/Domestic)

Cryopreserved (MN Mini)

Transgene: Ubiquitin C (UBC) promoter driving tdTomato
NSRRC:0032 NLS-UBC-eGFP Minnesota Mini Green Fluorescent Protein Cryopreserved Transgene: Ubiquitin C (UBC) promoter driving Nuclear Localized eGFP
NSRRC:0033 Onco-pig Minnesota Mini and Minnesota Mini/Domestic KRASG12D and p53R172H Live-limited (MN/Domestic)

Cryopreserved (MN Mini)

Transgene: CAG LoxP Stop driving KRASG12D and p53R172H
NSRRC:0034 DMD Yucatan DMD Cryopreserved Deletion of Exon 42 of DMD
NSRRC:0035 RAG2 KO Minnesota Mini RAG2 Live-limited (MN Mini)

Cryopreserved (MN mini/Domestic)

RAG2 Knockout
NSRRC:0036 BRCA knockdown outbred BRCA1 Cryopreserved Transgene: CSN2 promoter driving micro RNAs directed against BRAC1 and RASSF1
NSRRC:0037 CD55 into GGTA1 Minnesota Mini and Minnesota Mini/Domestic GGTA1 and CD55 Live-limited (MN/Domestic)

Cryopreserved (MN Mini)

GGTA1 knockout with a transgene for human decay-accelerating factor (CD55) inserted into GGTA1
NSRRC:0038 CD1D KO outbred CD1D Live CD1D knockout
NSRRC:0041 wild-type- White line outbred N/A Cryopreserved wildtype
NSRRC:0042 Wild-Type-Purple outbred N/A Cryopreserved wildtype
NSRRC:0043 Wild-type-Green outbred N/A Cryopreserved wildtype
NSRRC:0049 ELOVL4-Line 913 outbred ELOVL4 Cryopreserved Transgene: ELOVL4 Y270X with the enhanced yellow fluorescent protein
NSRRC:0050 ELOVL4-Line 301 outbred ELOVL4 Cryopreserved Transgene: ELOVL4 Y270X with the enhanced yellow fluorescent protein
NSRRC:0052 ELOVL4-Line 304 outbred ELOVL4 Cryopreserved Transgene: ELOVL4 Y270X with the enhanced yellow fluorescent protein
NSRRC:0057 CTRP outbred C1QTNF5 (CTRP) Cryopreserved Transgene: S163R mutation of pig CTRP (C1QTNF5)
NSRRC:0058 CTRP-Line 2 outbred C1QTNF5 (CTRP) Cryopreserved Transgene: S163R mutation of pig CTRP (C1QTNF5)
NSRRC:0059 Str8 mitochondrial localized eYGFP outbred Enhanced Yellow Fluorescent Protein Cryopreserved Transgene: male germ cell (STR8) tissue-specific expression of enhancing yellow fluorescent protein (EYFP)
NSRRC:0060 TMPRSS2 outbred TMPRSS2 Characterizing TMPRSS2 knockout via zygote injection of the CRISPR Cas-9 system.
NSRRC:0061 CD39 and CD55 into GGTA1 Minnesota Mini GGTA1 Cryopreserved GGTA1 knockout with human decay-accelerating factor (CD55) and CD39 transgenes inserted into GGTA1
NSRRC:0062 FAH outbred FAH Cryopreserved FAH Knockout via zygote injection of the CRISPR Cas-9 system.
NSRRC:0063 SMN domestic SMN Characterizing SMN Knockout
NSRRC:0064 APC Minnesota Mini APC Cryopreserved Heterozygous modification of the Adenomatous polyposis coli (APC) gene to induce colorectal polyps
NSRRC:0069 SIGLEC1/CD169
domestic SIGLEC1
Cryopreserved cells and semen Insertion of a transgene harboring neomycin resistance into the SIGLEC1 gene through homologous recombination, knocking out gene function. Obtained through somatic cell nuclear transfer and propagated by breeding. Homozygous and heterozygous available.
NSRRC:0070 ANPEP
domestic ANPEP
Cryopreserved cells and semen Knockout of gene function via zygote injection of the CRISPR Cas-9 system. Homozygous and heterozygous available.
NSRRC:0071 CD163
domestic CD163
Cryopreserved cells and semen Knockout of gene function via zygote injection of the CRISPR Cas-9 system. Homozygous and heterozygous available.
NSRRC:0072 ANTXR1
domestic ANTXR1
Cryopreserved  Monoallelic in-frame mutation via zygote injection of the CRISPR Cas-9 system. Available in semen and fetal fibroblast.
NSRRC:0075 FANCA
domestic FANCA
Live  KO of FANCA Exon 4 via zygote injection of the CRISPR Cas-9 system.
NSRRC:0076 FANCD2
domestic FANCD2
Cryopreserved cells and semen Monoallelic KO of FANCD2 via zygote injection of the CRISPR Cas-9 system. A biallelic modification is embryonic lethal.
NSRRC:0077 USH2A
domestic USH2A
Cryopreserved cells Both biallelic and monoallelic knockout of the USH2A gene via zygote injections of the CRISPR Cas-9 system. This induces Usher Syndrome Type 2. Available in fetal fibroblast.
NSRRC:0079 CLCA1
domestic CLCA1
Live KO of the CLCA1 gene via zygote injections of the CRISPR Cas-9 system, to reduce mucus production in the lungs.
NSRRC:0081 SAP130
domestic SAP130
Cryopreserved cells Monoallelic knockout of the SAP130 gene via zygote injections of the CRISPR Cas-9 system. A biallelic modification is embryonic lethal. Available in fetal fibroblast.
NSRRC:0085 FAH/RAG2
domestic FAH, RAG2
Cryopreserved cells A biallelic knockout of both FAH and RAG2 genes, using the CRISPR Cas-9 system in zygote injections and electroporation.
NSRRC:0086 GGTA1 KO/B4GALNT2 KO/B4GALNT2L KO with CD55 domestic GGTA1, B4GALNT2, B4GALNT2L Live-limited; also available by SCNT GGTA1 KO/B4GALNT2 KO/B4GALNT2L KO with a transgene for human decay-accelerating factor (CD55)
NSRRC:0093  APP domestic APP
Live-limited  Alzheimers model
NSRRC:0094  PSEN1 domestic  PSEN1 Live-limited Alzheimers model
NSRRC:0095  RAG2/IL2RG domestic  RAG2, IL2RG
Cryopreserved  Skid model
NSRRC:0096  IgH (Ig Heavy Chain)
domestic IgH
Cryopreserved  
NSRRC:0097  Large white x Landrace
domestic  N/A Cryopreserved  Wildtype, non-modified pigs.
NSRRC:0098  GDF9 domestic  GDF9 Live, cryopreserved cells, semen  Modification of the GDF9 gene via zygote injection of the CRISPR Cas-9 system. Resulting phenotype is a lack of folliculogenesis.

(Click on the Stock # link for additional information.)

PROCESS:

Receiving Investigator must:

Fill out and submit an On-Line Receiving Investigator Application Form.
Provide a Material Transfer Agreement (MTA) using the Institution MTA or the Governmental MTA form.

The NSRRC will then:

Obtain authorization from the Receiving Investigator’s Institution for animal shipment.
Ship animals to the Receiving Investigator’s Institution.
Bill the account. See the Distribution Fees Page for pricing.